Health Effects of Vegetables and Fruit: Assessing Mechanisms of Action in Human Experimental Studies
Epidemiologic data support the association between high intake of vegetables and fruits and low risk of chronic disease.There are several biologically plausible reasons why consumption of vegetables and fruit might slow or prevent the onset of chronic diseases. Vegetables and fruit are rich sources of a variety of nutrients, including vitamins, trace minerals, and dietary fiber, and many other classes of biologically active compounds. These phytochemicals can have complementary and overlapping mechanisms of action, including modulation of detoxification enzymes, stimulation of the immune system, reduction of platelet aggregation, modulation of cholesterol synthesis and hormone metabolism, reduction of blood pressure, and antioxidant, antibacterial, and antiviral effects.....................................
American Journal of Clinical Nutrition, Vol. 70, No. 3, 475S-490S, September 1999
A Comprehensive Approach
The Purification Program provides comprehensive nutritional (Whole Food Complexes) and botanical (Herbal) support to maintain proper functioning of the various detoxification pathways. By incorporating the nutrients mentioned above, it is able to address both phase I and phase II detoxification pathways.
Gastrointestinal support for detoxification is provided by Whey Protein, Psyllium Husk Powder, Rice Bran, Beet Root, Carrot Root, Oat Fiber, and Apple Pectin. Vitamins and minerals and amino acids required in phase II reactions such as L-glutamine, L-lysine HCL, glycine, L-carnitine and taurine, also support detoxification. Furthermore, specific ingredients such as milk thistle, citrus bioflavonoids and spanish black radish have been shown to aid in various aspects of detoxification. Cruciferous vegetables provide sulfur metabolites, contain selenium, protect against reactive oxygen species, and induce phase II enzymes. Also toxin binding is assisted with modified apple pectin.
Standard Process Purification Program
SP Cleanse
A powerful combination of over 20 whole foods and botanicals that possess detoxifying properties. They contain nutrients which support the body’s natural efforts to remove toxins and other waste materials.
- Encourages healthy kidney function
- Supports blood purification processes & lymphatic system function
- Encourages healthy gastrointestinal elimination
- Promotes healthy liver detoxification functions
- Barley Grass Powder – Source of chlorophyll and other phytonutrients that support the antioxidant system and toxin removal.
- Spanish Black Radish Root - Increases the activity of glutathione, quinone, and thioredoxin – enzymes involved in phase II detox; Great source of phytonutrient antioxidants such as C complex – protection against free radicals.
- Oregon Grape Root Powder - good source of antioxidants
- Fenugreek Seed Powder - cholesterol metabolisms; improve glucose tolerance by delaying carbohydrate digestion and absorption while increasing insulin activity.
- Juniper Berry Powder - natural diuretic; Essential oils that help the body excrete uric acid and other waste materials
- Red Clover Flower - promotes cleansing of the blood
- Apple Pectin - excellent source of natural fiber; Stimulate intestinal bacterial enzyme activity
- Burdock Root Powder - Natural diuretic to support healthy elimination through the kidneys
- Cayenne Pepper - Stimulate gastric secretions ; Supports liver detox by reducing oxidative stress; Reverses the depletion of glutathione in the liver
- Milk Thistle – contain flavanoids that are free radical scavengers; Hepatorestorative and Hepatoprotective – protection against toxins
- Globe Artichoke - Gallbladder and liver support; Support normal bile production and secretion; Globe Artichoke (Cynara) has a powerful effect on the production of bile and fat-digesting enzymes, stimulating liver functions and lowering cholesterol levels; Promotes digestion especially of fatty foods and normal bowel movement
- Dandelion Leaves - Healthy fluid levels ; Stimulate healthy urinary flow
- Tillandsia - Efficient chelating properties
- Broccoli, Kale, Brussel Sprouts - Contains phytochemicals that stimulate enzymatic activity for liver detoxification processes; Improve cholesterol metabolism and decrease markers of oxidative stress; Brassica vegetables provide high amounts of vitamin C and soluble fiber and contain multiple nutrients with potent cancer preventing properties: 3,3'-Diindolylmethane, sulforaphane and selenium
- Carrot Root Powder - Carrots contains a very complete nutrition to provide our body the essential enzymes, vitamins and minerals; source of B-vitamins, such as folic acid, a group of vitamin B, which has good effect to fight against free radicals (substances that cause cancer) in our body; source of Carotenoids, which can inversely affect insulin resistance and thus lower blood sugar.
A nutritional shake mix combining over 20 different whole foods ingredients to support the body during purification, as well as every day for a well-balanced diet.
- Provides multiple nutrient in a highly bio-available form
- Supports a healthy cardiovascular system
- Encourages healthy nervous system function
- Delivers strong antioxidant protection to promote cellular health
- Supports healthy digestive system function
- Supports healthy liver function
- Whey Protein - high in minerals & nutrients that offer a particularly high quality source of protein
- Buckwheat - rich in rutin that helps to support vascular walls
- Barley grass - rich in Chlorophyll which assists in the natural cleansing of impurities from the blood
- Alfalfa - contains saponins which support healthy blood
- Brown rice - contains a concentrated amount of B-complex vitamins to support healthy nerves & proper brain function
- Grape Seed & Red Wine Extracts - bio-available sources of antioxidants
- Kale & Brussels Sprouts - high in fiber, Indoles, minerals, and vitamins A, C, & E complexes
- Flax Meal Powder - contains soluble/insoluble fibers and provides a healthy dose of plant lignans assisting in immune function & inhibit abnormal cell growth
- Carrot Root Powder - Carrots contains a very complete nutrition to provide our body the essential enzymes, vitamins and minerals; source of B-vitamins, such as folic acid, a group of vitamin B, which has good effect to fight against free radicals (substances that cause cancer) in our body; source of Carotenoids, which can inversely affect insulin resistance and thus lower blood sugar.
Provides dietary fiber from botanical and other whole food sources, delivering powerful support to the gastrointestinal system and helping detoxify the body.
- Cleanses the gastrointestinal tract
- Encourages a healthy intestinal environment
- Supports & maintain gastrointestinal lining
- Stimulates proper gastric juice flow & peristalsis
- Maintains regular intestinal evacuation
- Enhances the cleansing activities of the liver
- Psyllium (husk) Powder - natural diuretic/stool softener; high in soluble fiber
- Collinsonia (root) Powder - promotes cleansing of the blood
- Apple Pectin - excellent source of natural fiber
- Fennel Seed - supports digestive environment & gastric healing
- Fenugreek Seed Powder - healthy digestion & cholesterol metabolism
- Contains more insoluble fiber which creates a feeling of fullness
- Encourages healthy intestinal bacteria growth
- Cleanses the gastrointestinal tract
- Promotes healthy blood glucose and lipid levels
- Enhances the cleansing activities of the liver
- Provides phytochemicals, vitamins, minerals, and essential amino acids
- Rice Bran - regulates healthy elimination with antioxidant qualities
- Beet Root - protects from free radical damage
- Carrot Root - aids in normal elimination
- Oat Fiber - enhances the growth of “good” bacteria in the intestines
- Apple Pectin - excellent source of natural fiber, aids in digestion and healthy bowel elimination
Contains five (5) organically grown whole food concentrates providing nutrients to help detoxify the liver and support the immune system.
- Provides vitamins, minerals, micronutrients, & other phytochemicals from natural, whole-food sources to promote nutritional balance.
- Supports healthy physical, mental, & emotional development.
- Supplies aggressive antioxidant protection to help maintain cellular health & stability.
- Assists with liver detoxification & promote the consistent removal of cellular debris.
- Buckwheat Juice Powder - natural diuretic/stool softener; high in soluble fiber
- Barley Grass Juice Powder - promotes cleansing of the blood
- Brussels Sprout Powder - excellent source of natural fiber
- Kale Powder - supports digestive environment & gastric healing
- Alfalfa Sprout Powder - healthy digestion & metabolism
1 Rogers SA. Chemical Sensitivity: Breaking the Paralyzing Paradigm. Internal Medicine World Report 1992; February 1-14:15-16.
2 Lawson L. Staying Well in a Toxic World. Chicago: The Nobel Press, Inc.; 1993.
3 Rogers SA. Chemical Sensitivity: Breaking the Paralyzing Paradigm. Internal Medicine World Report 1992; February 1-14:15-16.
4 Gibson PR. Multiple Chemical Sensitivity. Oakland, California: New Harbinger Publications, Inc.; 2000.
5 Lawson L. Staying Well in a Toxic World. Chicago: The Nobel Press, Inc.; 1993.
6 Pizzorno Jr JE, Murray MT. Textbook of Natural Medicine, 3rd. ed. Edinburgh: Churchill Livingstone; 2005.
7 Organic Food Standards and Labels: The Facts. The Organic National Food Program. Accessed on May 25, 2005 from http://www.ams.usda.gov/nop/Consumers/brochure.html.
8 Kristensen ES. Food safety in an organic perspective. 14th IFOAM Congress, Victoria, Canada; August 22nd 2002. Accessed on May 25, 2005 from http://orgprints.org/19/03/Kristensen_IFOAM_2002.ppt.
9 Magkos F, Arvaniti F, Zampelas A. Organic food: nutritious food or food for thought? A review of the evidence. International journal of food sciences and nutrition 2003; 54(5):357-71.
10 Holmboe-Ottesen G. [Better health with ecologic food?] Bedre helse med okologisk mat? Tidsskrift for den Norske laegeforening (Norway) 2004; 124(11):1529-31.
11 Bailey C. The Ultimate Fit or Fat. Boston: Houghton Mifflin; 2000
12 Murray Rk, Granner DK, Mayes PA, Rodwell VW. Harper's Biochemistry, 25th ed. New York: McGraw Hill; 200:780-786.
13 Lüllmann H. Mohr K, Ziegler A, Bieger D. Color Atlas of Pharmacology, 2nd ed. Stuttgart: Thieme; 2000:32-39.
14 Roundtree R. The Use of Phytochemicals in the Biotransformation and Elimination of Environmental Toxins. IN Medicines from the Earth 2003: Official Proceedings. Brevard, North Carolina: Gaia Herbal Research Institute; 2003:115-128.
15 Murray Rk, Granner DK, Mayes PA, Rodwell VW. Harper's Biochemistry, 25th ed. New York: McGraw Hill; 200:780-786.
16 Lüllmann H. Mohr K, Ziegler A, Bieger D. Color Atlas of Pharmacology, 2nd ed. Stuttgart: Thieme; 2000:32-39.
17 Murray Rk, Granner DK, Mayes PA, Rodwell VW. Harper's Biochemistry, 25th ed. New York: McGraw Hill; 200:780-786.
18 Lüllmann H. Mohr K, Ziegler A, Bieger D. Color Atlas of Pharmacology, 2nd ed. Stuttgart: Thieme; 2000:32-39.
19 Vailati A, Aristia L, Sozze E, et al. Randomized open study of the dose-affect relationship of a short course of IdB 1016 in patients with viral or alcoholic hepatitis. Fitoterapia 1993; 64:219-27.
20 Lirussi F, Okolicsanyi L. Cytoprotection in the nineties: experience with ursodeoxycholic acid and silymarin in chronic liver disease. Acta Physiol Hung 1992; 80:363-7
21 Magliulo E, Gagliardi B, Fiori GP. Results of a double blind study on the effect of silymarin in the treatment of acute viral hepatitis carried out at two medical centers. Med Klin 1978; 73:1060-5.
22 Bode JC, Schmidt U, Durr HK. Silymarin for the treatment of acute viral hepatitis? Report of a controlled trial. Med Klin 1977; 72:513-8.
23 Schuppan D, Strösser W, Burkard G, Walosek G. Legalon® lessens fibrosing activity in patients with chronic liver diseases. Zeits Allgemeinmed 1998; 74:577-84.
24 Campos R, Garido A, Guerra R, et al. Silybin dihemisuccinate protects against glutathione depletion and lipid peroxidation induced by acetaminophen on rat liver. Planta Med 1989;55:417-419.
25 Valenzuela A, Aspillaga M, Vial S, Guerra R. Selectivity of silymarin on the increase of the glutathione content in different tissues of the rat. Planta Med 1989; 55(5):420-2.
26 Crinnion WJ. Environmental Medicine, Part 2 - Health Effects of and Protection from Ubiquitous Airborne Solvent Exposure. Alternative Medicine Review 2000; 5(2):133-143
27 Blumenthal M. Herbal Medicine, Expanded Commission E Monographs, 1st ed. Austin: American Botanical Council; 2000.
28 Brinker F. Herb Contraindications and Drug Interactions, 2nd ed. Sandy (OR): Eclectic Med; 1998.
29 Bishayee A, Sarkar A, Chatterjee M. Hepatoprotective activity of carrot (Daucus carota L.) against carbon tetrachloride intoxication in mouse liver. Journal of Ethnopharmacology 1995; 47(2): 69-74.
30 Kiyofumi N, et al. Potent anti-obese principle from Rosa canina: structural requirements and mode of action of trans-tiliroside. Bioorganic & medicinal chemistry letters 2007; 17(11):3059-64.
31 Taraxaci folium: Dandelion Leaf. March 1996: Taraxaci folium pp. 1-6. IN ESCOP Monographs: The Scientific Foundation for Herbal Medicinal Products, 2nd ed. Stuttgart: Thieme; 2003.
32 Felter WF. The Eclectic Materia Medica, Pharmacology and Therapeutics. Online version http://www.ibiblio.org/herbmed/eclectic/felter/agropyron.html; 1922.
33 Petersen FJ. Materia Medica and Clinical Indications. Online version http://www.ibiblio.org/herbmed/eclectic/petersen/agropyron.html; 1905.
34 Ellingwood F. The American Materia Medica, Therapeutics and Pharmacognosy. Online version http://www.ibiblio.org/herbmed/eclectic/ellingwood/agropyron.html; 1919.
35 Hoffman D. The Herbal Handbook: A User's Guide to Medical Herbalism. Rochester, VT: Healing Arts Press; 1988.
36 Burdock Root. Natural Herbs Guide. 2008. Retrieved on June 6, 2008 from http://www.naturalherbsguide.com/burdock.html.
37 Lin CC, Lin JM, Yang JJ, et al. Anti-inflammatory and radical scavenge [sic] effects of Arctium lappa. Am J Chin Med 1996;24:127-37.